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IF:7.7!恭喜南京医科大学用机器学习拿下一区!思路超简单!

  • 2026-04-09 09:32:54
IF:7.7!恭喜南京医科大学用机器学习拿下一区!思路超简单!

新的一年！南京医科大学预测模型又上分！

IF：7.7/双一区

文章题目：按左心室大小标准化的QRS波群时限：消除性别特异性差异并预测心脏再同步治疗结局

研究背景

CRT是心衰伴电失同步患者的关键治疗手段，但存在显著性别特异性疗效差异，传统QRSd评估受心室大小影响，难以精准反映电失同步程度。现有评估体系不足以解释该差异，亟需更优指标优化CRT患者筛选与疗效预测。

研究方法

本多中心回顾性研究纳入602例接受CRT的患者，提取QRSd与LVEDD计算比值，采用Cox回归、ROC曲线、结构方程模型等，分析其对复合终点的预测价值及性别差异介导机制。

26年预测模型发文量已超6000篇🔥

广东、山东、江苏等地医生都在发

想了解更多内容，咨询科研顾问了解👇

部分研究结果

患者基线特征

女性患者心脏更小，QRSd/LVEDD比值更高，LVEF更高，房颤比例更低，LBBAP比例更高。

QRSd/LVEDD独立预测与中介效应

QRSd/LVEDD与结局呈剂量-反应关系。性别完全通过QRSd/LVEDD介导对结局的影响，直接效应不显著。

QRSd/LVEDD vs QRSd预测性能

QRSd/LVEDD预测主要终点的AUC显著高于QRSd，预测心衰住院AUC也更高，临床净获益更高。

文
章
小
结

研究结果表明，QRSd/LVEDD可消除CRT疗效的性别差异，且预测效能优于QRSd。未来需开展多中心前瞻性研究，验证其在不同CRT模式、QRSd区间患者中的适用性，优化cutoff值，纳入机器学习模型推广，助力精准筛选CRT获益人群。

如果你也想要复现选题，但苦于自己科研基础弱，总踩坑，热点把握度也低...

不如选择把病例交给专业团队，全程多v1服务，建群沟通创新方案，辅助科研成果产生！

白塔临床预测模型服务

💪甄选创新选题：团队专家在你的评估疾病方向后，会运用流行病学和循证医学方法，结合当前热点，高效确定创新选题！

部分可做方向👇

💪团队专家经验丰富：专家是复旦等名校医学硕博，临床研究经验丰富。按高分期刊标准设计方案，协助合作过的医生基本都能发上2~5分期刊。

辅助成果产出→

注意！各科室方向的创新选题数量有限

立即咨询抢占优质选题，确保高IF值👇

💪与多家三甲医院长期合作：17年科研协助经验，每年有广州、江苏、上海等300+三甲医生发来好评！

目前我们已利用白塔专病库系统

成功构建100+预测模型，合作50+三甲医院

只要手中有这8类数据，做预测模型so easy！

数据不够，还有TCGA、TCIA等公共数据库填补

长按识别海报二维码，抓紧咨询科研顾问👇

本文来自网友投稿或网络内容，如有侵犯您的权益请联系我们删除，联系邮箱：wyl860211@qq.com 。

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  1. CONNECT:[ UseTime:0.000795s ] mysql:host=127.0.0.1;port=3306;dbname=b460;charset=utf8mb4
  2. SHOW FULL COLUMNS FROM `fenlei` [ RunTime:0.000930s ]
  3. SELECT * FROM `fenlei` WHERE `fid` = 0 [ RunTime:0.000378s ]
  4. SELECT * FROM `fenlei` WHERE `fid` = 63 [ RunTime:0.000277s ]
  5. SHOW FULL COLUMNS FROM `set` [ RunTime:0.000510s ]
  6. SELECT * FROM `set` [ RunTime:0.000206s ]
  7. SHOW FULL COLUMNS FROM `article` [ RunTime:0.000614s ]
  8. SELECT * FROM `article` WHERE `id` = 501739 LIMIT 1 [ RunTime:0.000503s ]
  9. UPDATE `article` SET `lasttime` = 1775895464 WHERE `id` = 501739 [ RunTime:0.002293s ]
  10. SELECT * FROM `fenlei` WHERE `id` = 65 LIMIT 1 [ RunTime:0.000246s ]
  11. SELECT * FROM `article` WHERE `id` < 501739 ORDER BY `id` DESC LIMIT 1 [ RunTime:0.000462s ]
  12. SELECT * FROM `article` WHERE `id` > 501739 ORDER BY `id` ASC LIMIT 1 [ RunTime:0.000768s ]
  13. SELECT * FROM `article` WHERE `id` < 501739 ORDER BY `id` DESC LIMIT 10 [ RunTime:0.000776s ]
  14. SELECT * FROM `article` WHERE `id` < 501739 ORDER BY `id` DESC LIMIT 10,10 [ RunTime:0.000978s ]
  15. SELECT * FROM `article` WHERE `id` < 501739 ORDER BY `id` DESC LIMIT 20,10 [ RunTime:0.001259s ]
0.084635s