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4月22日南京农业大学 | 上科大生命学院刘雪松、窦坤老师前往交流

  • 2026-05-09 11:25:29
4月22日南京农业大学 | 上科大生命学院刘雪松、窦坤老师前往交流
南京农业大学
2026
南京站
  上海科技大学
生命学院

  【 南京农业大学 】

讲座题目：基因组中的暗物质——“跳跃基因”

时间：2026年4月22日（周三）14：00

地点：南京农业大学（卫岗校区）教学楼B109教室

主讲人：上海科技大学生命学院 窦坤

             上海科技大学生命学院 刘雪松
刘雪松
副教授，研究员，博士生导师
研究方向：大数据人工智能与肿瘤免疫治疗
教育经历：
1998/09—2002/07，武汉大学，学士
2002/09—2007/07，中国科学院上海生命科学研究院健康科学研究所，博士
博士后及工作经历：
2008/10—2015/05，美国哈佛大学，博士后
2015/06—2022/09，上海科技大学，生命科学与技术学院，助理教授（TENURE-TRACK）
2022/09—至今，上海科技大学，生命科学与技术学院，副教授（TENURED）
癌症是复杂系统疾病，包含基因组、转录组、蛋白组等多模态组学数据的整合分析是实现肿瘤精准诊断与治疗的关键。本实验室研究聚焦肿瘤精准分型标志物研发、肿瘤特异性靶点发掘以及靶点特异性抗体或TCR的从头AI设计验证与应用。综合运用多模态整合AI、生成式AI技术，同时结合生化细胞与小鼠模型实验验证，实现“肿瘤分型—靶点发掘—抗体及TCR药物AI设计与验证”的闭环。
窦坤
助理教授，研究员，博士生导师
研究方向：转座子生物学、表观遗传
教育经历：
2005/09—2009/06，湖南大学，学士
2009/09—2014/06，北京生命科学研究所（NIBS）/北京师范大学，博士
博士后及工作经历：
2014/07—2015/08，北京生命科学研究所，博士后
2015/08—2020/01，卡耐基科学研究所，博士后
2020/01—至今，上海科技大学，生命科学与技术学院，助理教授 (TENURE-TRACK)
转座子，又称跳跃基因，是一类广泛“寄生”于真核生物的“自私基因”，占人类基因组45%以上，其激活可引起基因组不稳定性，引发疾病甚至癌症。因此进行转座子的研究对人类健康有重要意义。果蝇作为遗传工具丰富的模式生物为我们的研究提供了便利。本实验室以果蝇为主要模式生物，辅以细胞系和小鼠，挖掘转座元件调控的保守机制，进行转座子生物学与表观遗传调控研究，并重点关注宿主与转座子的互作。

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  1. CONNECT:[ UseTime:0.001167s ] mysql:host=127.0.0.1;port=3306;dbname=b460;charset=utf8mb4
  2. SHOW FULL COLUMNS FROM `fenlei` [ RunTime:0.001577s ]
  3. SELECT * FROM `fenlei` WHERE `fid` = 0 [ RunTime:0.002282s ]
  4. SELECT * FROM `fenlei` WHERE `fid` = 63 [ RunTime:0.026104s ]
  5. SHOW FULL COLUMNS FROM `set` [ RunTime:0.001510s ]
  6. SELECT * FROM `set` [ RunTime:0.004617s ]
  7. SHOW FULL COLUMNS FROM `article` [ RunTime:0.001521s ]
  8. SELECT * FROM `article` WHERE `id` = 536527 LIMIT 1 [ RunTime:0.002462s ]
  9. UPDATE `article` SET `lasttime` = 1779837029 WHERE `id` = 536527 [ RunTime:0.012515s ]
  10. SELECT * FROM `fenlei` WHERE `id` = 65 LIMIT 1 [ RunTime:0.000747s ]
  11. SELECT * FROM `article` WHERE `id` < 536527 ORDER BY `id` DESC LIMIT 1 [ RunTime:0.001140s ]
  12. SELECT * FROM `article` WHERE `id` > 536527 ORDER BY `id` ASC LIMIT 1 [ RunTime:0.006976s ]
  13. SELECT * FROM `article` WHERE `id` < 536527 ORDER BY `id` DESC LIMIT 10 [ RunTime:0.002073s ]
  14. SELECT * FROM `article` WHERE `id` < 536527 ORDER BY `id` DESC LIMIT 10,10 [ RunTime:0.007537s ]
  15. SELECT * FROM `article` WHERE `id` < 536527 ORDER BY `id` DESC LIMIT 20,10 [ RunTime:0.005895s ]
0.255551s